3Rs INFO HUB

Dr. Ronaghan gives a review of lung test
models and goes into 2D and 3D models as replacement methods and the benefits of the use of human primary airways epithelial cells.

In this video the culture of primary airway epithelia cells with Air-Liquid-Interface cultures is presented. The model system is used to study respiratory virus infections.

Test your knowledge about the 3Rs in lung epithelia model research.

An replacement in vitro-based integrated
approach for smoking toxicity assessment is presented. The framework, used models and research data are discussed.

Presentation about production, use and performance of 3D ex vivo models based on precision-cut lung slices (PCLS) for toxicity testing as a replacement method.

The article summarizes in vitro and in silico methods that can be used for the assessment of inhalation toxicity and mentions eey events and testing strategies.

Test your knowledge about the lung and inhalation toxicology.