3Rs INFO HUB

The video provides a summary of the embryo development and the different stages of embryological development from day 1 to 22. (2020)

Here you will learn more about the basics of reproductive toxicology including teratogens and mother-to-child-transmission. (2022)

Test your knowledge about the 3Rs in reproductive toxicology.

Zebrafish embryos serve a a model in reproductive and developmental toxicity studies.
For regulatory purposes, the International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use (ICH) needs to implement 3R methods into the ICH guidelines.
(2021, 20 min)

The review summarizes the recent developments in the field of human teratogenic assays.

The embryonic stem cell test (EST) is an validated method for evaluation of embryotoxic potential. As non-animal methods the EST is performed by using only permanent cell lines. (2016)

Test your knowledge about the 3Rs in reprotox research.